This course provides a foundation of knowledge about the human body in health and disease. It gives an overview of important concepts on the biological mechanisms of disease at the cellular, individual, and population/community levels. The course will focus on a natural progression in the development of health and disease, moving from a discussion of the cell, to the individual, and finally, to specific infectious or chronic disease states and processes. The role of the community in public health will be emphasized. This course is designed to provide a good foundation in the mechanisms of health and disease. Furthermore, each lecture will offer insights into current public health topics and research trends. Each lecture will address the following: 1) specific mechanisms of health and disease; 2) topics of special public health importance, and 3) a scientific update on research in the news.